Welcome to TARDIS's documentation!
===================================

**TARDIS** (TArget pRioritization toolkit for CRISPR Data In Spatial-omics) is a model based toolkit for tissue-specific CRISPR knockout screening analysis.

.. admonition:: Citation

   For usage, please refer to the CELL paper `Uncovering Spatially Resolved Functional Genomics with CRISPR Screen Sequencing <https://www.cell.com/cell/fulltext/S0092-8674(26)00516-7>`_..
   Please cite the paper when using the toolkit.

.. image:: ../_images/main_tardis_desc.jpg
   :alt: TARDIS Overview
   :align: center
   :width: 1200px



**TARDIS** is a free, open-source software for both python and R environment users under the MIT license.

Official documentation can be found `here <https://tardis-tutorial.readthedocs.io/en/latest/>`_.

Refer to our **SPAC-seq** website for data download and analysis at `https://spac.pku-genomics.org <https://spac.pku-genomics.org>`_.

Check out the :doc:`Usage` section for further information, including
how to :ref:`Installation` the project.

.. note::

   This project is under active development.

Contents
--------

.. toctree::

   Installation
   Preprocessing
   NMF
   Cellcharter
   GlobalModule
   LocalModule
   Plot
   Tutorial

Contacts
--------

If you have any questions or suggestions, please feel free to contact me at `Barry Wang <barry_2001@stu.pku.edu.cn>`_.